Cellium, our first New Botanical Entity, stands on
a novel, patented, 3-level mechanism of action

Increased resistance to apoptosis1,2

Cellium restores (before 3 months) number of cells expressing Bcl-2 in AGA subjects to levels close to those observed in healthy controls.


It promotes significantly (+74%) Langherans cells in epidermis, which modulate immune response and exercise anti-inflammatory functions.

Collagen content and remodeling3

Collagen around the follicle increased by 79,93% within 4 months after application start. Collagen fibers are thicker and remodeled.

(1) Cellium® GC: evaluation of a new natural active ingredient in 210 mg/ml topical solution, through scalp biopsy - Surg Cosmet Dermatol 3(2):123-28 (2011) - Cucé L et al.
(2) Evaluation of Bcl-2 Level through Biopsies of the Scalp in Healthy Subjects - Dermatology Service of UNISA – Universidade de Santo Amaro ‎ São Paulo, SP – Brasil
(3) Clinical Efficacy by Biopsies on Alopecia Male Patients – CEBA4 - 4 months - Departamento de Dermatologia e Servico de Inestetica – CEP 01246-903 - Sao Paulo, SP - Brasil